Located in the heart of Phoenix, Ariz., St. Joseph's Hospital and Medical Center is a 586-bed, not-for-profit hospital that provides a wide range of health, social and support services with special advocacy for the poor and underserved. St. Joseph's is a nationally recognized center for quality tertiary care, medical education and research. It includes the internationally renowned Barrow Neurological Institute, the Muhammad Ali Parkinson Center, the Norton Thoracic Institute, a campus of Creighton University's Medical School and the first Level I Trauma Center in Arizona verified by the American College of Surgeons. U.S. News & World Report routinely ranks St. Joseph's among the best hospitals in the United States for neurology and neurosurgery. For more information please visit our website at https://www.dignityhealth.org/arizona/locations/stjosephs.
The Barrow Neurological Institute (BNI) (Phoenix, AZ), has been ranked in the top 10 best hospitals for neurology and neurosurgery since the US News and World Reports began reporting such data. The BNI leads the largest pharmacokinetics- (PK) and pharmacodynamics (PD)-driven clinical trials program for primary brain tumors in the United States. To support the clinical trial program, a centralized Pharmacology Core laboratory is being developed with the mission of providing state-of-the-art bioanalytic technology and a broad range of pharmacology expertise to enable evaluation of critical pharmacological endpoints in clinical trials.
The BNI Pharmacology Core is seeking a highly motivated bioanalytical scientist responsible for the quantitative analysis of small molecule drugs, metabolites, and endogenous chemicals in biological samples to support clinical and preclinical drug metabolism and pharmacokinetic studies.
Key responsibilities include:
• Development, validation, and implementation of LC-MS//MS methods to quantitatively determine small molecule drugs and metabolites in biological samples to support preclinical and clinical drug metabolism and pharmacokinetic studies;
• Development and implementation of novel sample preparation and separation strategies;
• Development and implementation of LC-MS/MS methods to identify chemical structures of unknown metabolites.
• A successful candidate should have 2+ years of experience in the development and implementation of LC-MS/MS based bioanalytical methods.
• The candidate should have demonstrated expertise in biological sample preparation.
• The candidate should have a demonstrated ability to think strategically, anticipate and identify key issues, facilitate problem solving and resolution.
• The candidate should have excellent collaboration and communication skills, both written and oral.
Three (3) years of laboratory or clinical research at the post-doctoral level with an interest in a faculty member's line of study required.
Laboratory or clinical technical and/or interpersonal expertise as appropriate required
Proficient with basic computer, mathematical, scientific, reasoning, and oral and written communication skills as appropriate required.
Beyond minimum required, experience largely functioning independently writing research reports concerning own work and familiarity with a biomedical discipline preferred.
Technical and/or conceptual mastery in a relevant field preferred. Expertise in basic computer, mathematical, scientific, reasoning, and oral and written communication skills as appropriate preferred.
Ph.D., in Analytical Chemistry, Biochemistry, Pharmaceutical Sciences, pharmacology, or a related discipline.
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